"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2021-10-26T21:58:42Z"
data-video-section="health"
data-canonical-url="https://www.cnn.com/videos/health/2021/10/26/dr-christakis-intv-pfizer-fda-children-5-to-11-vaccinated-school-sot-lead-vpx.cnn"
data-branding-key=""
data-video-slug="Dr. Christakis intv pfizer fda children 5 to 11 vaccinated school sot lead vpx"
data-first-publish-slug="Dr. Christakis intv pfizer fda children 5 to 11 vaccinated school sot lead vpx"
data-video-tags="children,children's health,communicable disease control,companies,demographic groups,families and children,family members and relatives,government organizations - us,health and health care (by demographic group),health and medical,maternal and child health,pediatric vaccinations,pfizer inc,population and demographics,public health,society,us department of health and human services,us federal departments and agencies,us food and drug administration,vaccination and immunization"
data-details="">
Video Ad Feedback
Doctor: This is why I want children to get vaccinated at school
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2021-10-26T21:58:42Z"
data-video-section="health"
data-canonical-url="https://www.cnn.com/videos/health/2021/10/26/dr-christakis-intv-pfizer-fda-children-5-to-11-vaccinated-school-sot-lead-vpx.cnn"
data-branding-key=""
data-video-slug="Dr. Christakis intv pfizer fda children 5 to 11 vaccinated school sot lead vpx"
data-first-publish-slug="Dr. Christakis intv pfizer fda children 5 to 11 vaccinated school sot lead vpx"
data-video-tags="children,children's health,communicable disease control,companies,demographic groups,families and children,family members and relatives,government organizations - us,health and health care (by demographic group),health and medical,maternal and child health,pediatric vaccinations,pfizer inc,population and demographics,public health,society,us department of health and human services,us federal departments and agencies,us food and drug administration,vaccination and immunization"
data-details="">
Video Ad Feedback
Doctor: This is why I want children to get vaccinated at school
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2022-10-20T11:32:56Z"
data-video-section="world"
data-canonical-url="https://www.cnn.com/videos/world/2022/10/20/china-covid-protest-new-york-selina-wang-pkg-ovn-intl-contd-ldn-vpx.cnn"
data-branding-key=""
data-video-slug="china covid protest new york selina wang pkg ovn intl contd ldn vpx"
data-first-publish-slug="china covid protest new york selina wang pkg ovn intl contd ldn vpx"
data-video-tags="arts and entertainment,asia,business and industry sectors,business, economy and trade,chemical industry and chemicals,chemicals and environment,china,communicable disease control,continents and regions,diseases and disorders,east asia,environment and natural resources,epidemics and outbreaks,graffiti art,health and medical,infectious diseases,isolation and quarantine,public health,toxic and hazardous substances,visual arts,coronavirus,life forms,microscopic life,respiratory diseases,viruses,international relations,international relations and national security"
data-details="">
Video Ad Feedback
Artist wears 27 hazmat suits to protest China's policies
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2022-10-03T04:07:55Z"
data-video-section="travel"
data-canonical-url="https://www.cnn.com/videos/travel/2022/10/01/hong-kong-attempts-to-revitalize-tourism-reopening-lu-stout-pkg-vpx.cnn"
data-branding-key=""
data-video-slug="hong kong attempts to revitalize tourism reopening lu stout pkg vpx"
data-first-publish-slug="hong kong attempts to revitalize tourism reopening lu stout pkg vpx"
data-video-tags="asia,china,continents and regions,coronavirus,coronavirus pandemic,diseases and disorders,east asia,epidemics and outbreaks,health and medical,hong kong,infectious diseases,kristie lu stout,life forms,microscopic life,misc people,public health,respiratory diseases,taiwan,tourism,travel and tourism,viruses"
data-details="">
Video Ad Feedback
See how Hong Kong is trying to revitalize itself after Covid-19
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2022-09-20T19:06:18Z"
data-video-section="business"
data-canonical-url="https://www.cnn.com/videos/media/2022/09/20/late-night-reaction-joe-biden-pandemic-is-over-orig-ht.cnn-business"
data-branding-key=""
data-video-slug="late night reaction Joe Biden pandemic is over orig ht"
data-first-publish-slug="late night reaction Joe Biden pandemic is over orig ht"
data-video-tags=""
data-details="">
Video Ad Feedback
See late night reactions to President Biden claiming pandemic over
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2022-09-05T13:32:45Z"
data-video-section="health"
data-canonical-url="https://www.cnn.com/videos/health/2022/09/05/long-covid-brain-fog-video-game-treatment-gupta-pkg-newday-vpx.cnn"
data-branding-key=""
data-video-slug="long covid brain fog video game treatment gupta pkg newday vpx"
data-first-publish-slug="long covid brain fog video game treatment gupta pkg newday vpx"
data-video-tags="business and industry sectors,business, economy and trade,computer science and information technology,experimentation and research,human subjects,misc people,sanjay gupta,science,software and applications,technology,video games"
data-details="">
Video Ad Feedback
Dr. Gupta: This treatment for 'brain fog' from long-Covid just might surprise you
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2022-07-27T14:01:41Z"
data-video-section="world"
data-canonical-url="https://www.cnn.com/videos/world/2022/07/27/covid-origins-wuhan-market-live-jiang-newday-intl-ldn-vpx.cnn"
data-branding-key=""
data-video-slug="covid origins wuhan market live jiang newday intl ldn vpx"
data-first-publish-slug="covid origins wuhan market live jiang newday intl ldn vpx"
data-video-tags="asia,beijing,business and industry sectors,business, economy and trade,central china,china,computer chips,computer equipment,computer science and information technology,consumer products,continents and regions,coronavirus,diseases and disorders,east asia,experimentation and research,farmers markets,food and drink,food products,health and medical,hubei province,infectious diseases,kinds of foods and beverages,life forms,memory technology,microscopic life,respiratory diseases,retail and wholesale trade,science,seafood,street markets and traders,technology,viruses,wuhan"
data-details="">
Video Ad Feedback
New studies suggest Covid-19 likely originated from Wuhan wet market
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2022-07-21T15:19:38Z"
data-video-section="politics"
data-canonical-url="https://www.cnn.com/videos/politics/2022/07/21/jill-biden-sot-joe-biden-positive-coronavirus-nr-vpx.cnn"
data-branding-key=""
data-video-slug="jill biden sot joe biden positive coronavirus nr vpx"
data-first-publish-slug="jill biden sot joe biden positive coronavirus nr vpx"
data-video-tags=""
data-details="">
Video Ad Feedback
Jill Biden speaks out after President Biden contracts Covid-19
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2022-07-15T12:31:33Z"
data-video-section="business"
data-canonical-url="https://www.cnn.com/videos/business/2022/07/15/china-economy-covid-wang-henan-bank-pkg-intl-hnk-vpx.cnn"
data-branding-key=""
data-video-slug="China economy covid wang henan bank pkg intl hnk vpx"
data-first-publish-slug="China economy covid wang henan bank pkg intl hnk vpx"
data-video-tags="asia,banking, finance and investments,beijing,business, economy and trade,china,continents and regions,coronavirus,diseases and disorders,east asia,economic migration,economic policy,economy and economic indicators,employment and income status,epidemics and outbreaks,globalization,government and public administration,government bodies and offices,health and medical,immigration,immigration, citizenship and displacement,infectious diseases,international relations and national security,labor and employment,labor sector performance,life forms,local governments,microscopic life,migrant workers,personal finance,politics,public debt,public finance,public health,respiratory diseases,social and economic status,society,trade and development,viruses,unemployment,workers and professionals,demographic groups,families and children,males (demographic group),parents and parenting,population and demographics,economic conditions,economic crisis,economic decline"
data-details="">
Video Ad Feedback
'I'm losing my mind': Chinese depositor loses life savings in bank
"
data-check-event-based-preview=""
data-is-vertical-video-embed="false"
data-network-id=""
data-publish-date="2022-07-13T12:50:23Z"
data-video-section="health"
data-canonical-url="https://www.cnn.com/videos/health/2022/07/13/dr-anthony-fauci-coronavirus-new-variant-immunity-sot-newday-vpx.cnn"
data-branding-key=""
data-video-slug="dr anthony fauci coronavirus new variant immunity sot newday vpx"
data-first-publish-slug="dr anthony fauci coronavirus new variant immunity sot newday vpx"
data-video-tags="anthony fauci,diseases and disorders,health and medical,infectious diseases,life forms,microscopic life,misc people,viruses"
data-details="">
Video Ad Feedback
Dr. Fauci explains why new BA.5 subvariant is concerning
Vaccine maker Pfizer said Friday that trials of its vaccine in children ages 2 to 5 show that it did not provide the expected immunity in kids this age, and it is adding a third dose to the regimen.
The company decided to add the third dose for all children and babies ages 6 months to 5 years after its independent outside advisers took a look at the data so far.
It showed that two child-sized doses of the Pfizer/BioNtech vaccine were not producing the expected immunity in the 2- to 5-year-olds, although they were doing so for the babies up to age 2.
So the company said it would “amend” the trial to add a third dose.
“The study will now include evaluating a third dose of 3 micrograms at least two months after the second dose of the two-dose series to provide high levels of protection in this young age group,” it said.
Pfizer had taken the dosage size down for children. For the 12 and up age group, the dose is 30 micrograms of vaccine. Pfizer and BioNTech stepped this down to 10 micrograms for kids 5 to 11 and took it even lower, to 3 micrograms a dose, for the youngest children.
Early tests had indicated that this small dose would produce a strong immune response in the children and minimize the risk of side effects.
But the interim data – which the independent Data and Safety Monitoring Board can see without giving details to the company or investigators – indicates this small dose regimen did not produce the expected immune response in the 2- to 5-year-olds.
“No safety concerns were identified and the 3 microgram dose demonstrated a favorable safety profile in children 6 months to under 5 years of age,” Pfizer said in a statement.
“The decision to evaluate a third dose of 3 micrograms for children 6 months to under 5 years of age reflects the companies’ commitment to carefully select the right dose to maximize the risk-benefit profile,” it added.
“If the three-dose study is successful, Pfizer and BioNTech expect to submit data to regulators to support an Emergency Use Authorization (EUA) for children 6 months to under 5 years of age in the first half of 2022.”
The company will also test third doses in older children, who do not yet have authorization for booster doses of vaccine. Kids ages 5 to 11 and 12 to 15 will get full-dose third shots in the trials.
The changes probably mean a delay in authorization for vaccines for younger children, Dr. Anthony Fauci said.
“I think out of necessity, Erica, it’s going to make the time frame for when we get an emergency use authorization for children that young, it won’t be likely until the second quarter of 2022, and we were hoping it would be in the first quarter,” Fauci, who is director of the National Institute of Allergy and Infectious Diseases, told CNN’s Erica Hill.
“But at least from what Pfizer is saying, by the time they get all of the necessary data and go through all of the procedure of getting an emergency use authorization, unfortunately, it’s not going to be until the second quarter,” he added.
“But you want to really get the right dose and the right regimen for the children. So although you don’t like there to be a delay, you want to get it right, and that’s what they’re talking about. “
